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Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes  for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry

Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico  Characterization of a Novel Kappa-Opioid Receptor Antagonist
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist

Kappa opioid receptor signaling in the brain: Circuitry and implications  for treatment - ScienceDirect
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect

Narcotic Addiction in Failed Back Surgery Syndrome - Yuan-Chuan Chen,  Ching-Yi Lee, Shiu-Jau Chen, 2019
Narcotic Addiction in Failed Back Surgery Syndrome - Yuan-Chuan Chen, Ching-Yi Lee, Shiu-Jau Chen, 2019

Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and  Back
Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and Back

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience

Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical  Role of the Dynorphin/Kappa Opioid Receptor System
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Opioid agonists, mixed agonist-antagonists and partial agonists | Osmosis
Opioid agonists, mixed agonist-antagonists and partial agonists | Osmosis

Focusing on the Opioid System for Addiction Biomarker Discovery: Trends in  Molecular Medicine
Focusing on the Opioid System for Addiction Biomarker Discovery: Trends in Molecular Medicine

Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands:  Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience

A unique natural selective kappa-opioid receptor agonist, salvinorin A, and  its roles in human therapeutics - ScienceDirect
A unique natural selective kappa-opioid receptor agonist, salvinorin A, and its roles in human therapeutics - ScienceDirect

Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective  short-acting antagonist, during chronic extended access cocaine  self-administration and re-exposure in rat | Request PDF
Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat | Request PDF

Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in  Compulsive Behaviors
Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors

Selective kappa opioid antagonists for treatment of addiction, are we there  yet? | Semantic Scholar
Selective kappa opioid antagonists for treatment of addiction, are we there yet? | Semantic Scholar

A systematic review on the kappa opioid receptor and its ligands: New  directions for the treatment of pain, anxiety, depression, and drug abuse -  ScienceDirect
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect

Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine  Dependence - ScienceDirect
Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine Dependence - ScienceDirect

Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic  Targets: Recent Progress and Future Perspective
Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic Targets: Recent Progress and Future Perspective

Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse |  National Institute on Drug Abuse (NIDA)
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse | National Institute on Drug Abuse (NIDA)

Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class  of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink
Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink

Frontiers | A Review of the Therapeutic Potential of Recently Developed G  Protein-Biased Kappa Agonists
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists

Antagonist for the Kappa Opioid Receptor - Probe Reports from the NIH  Molecular Libraries Program - NCBI Bookshelf
Antagonist for the Kappa Opioid Receptor - Probe Reports from the NIH Molecular Libraries Program - NCBI Bookshelf

Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic  Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist  or Antagonist Function with Reduced Risk of Tolerance and Addiction
Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction

The Therapeutic Potential of κ-Opioids for Treatment of Pain and Addiction  | Neuropsychopharmacology
The Therapeutic Potential of κ-Opioids for Treatment of Pain and Addiction | Neuropsychopharmacology

Untangling the complexity of opioid receptor function |  Neuropsychopharmacology
Untangling the complexity of opioid receptor function | Neuropsychopharmacology